A Span-Extraction Dataset for Chinese Machine Reading Comprehension

Machine Reading Comprehension (MRC) has become enormously popular recently and has attracted a lot of attention. However, the existing reading comprehension datasets are mostly in English. In this paper, we introduce a Span-Extraction dataset for Chinese machine reading comprehension to add language diversities in this area. The dataset is composed by near 20,000 real questions annotated on Wikipedia paragraphs by human experts. We also annotated a challenge set which contains the questions that need comprehensive understanding and multi-sentence inference throughout the context. We present several baseline systems as well as anonymous submissions for demonstrating the difficulties in this dataset. With the release of the dataset, we hosted the Second Evaluation Workshop on Chinese Machine Reading Comprehension (CMRC 2018). We hope the release of the dataset could further accelerate the Chinese machine reading comprehension research. Resources are available: https://github.com/ymcui/cmrc2018Comment: 6 pages, accepted as a conference paper at EMNLP-IJCNLP 2019 (short paper

Time Series Outlier Detection Based on Sliding Window Prediction

In order to detect outliers in hydrological time series data for improving data quality and decision-making quality related to design, operation, and management of water resources, this research develops a time series outlier detection method for hydrologic data that can be used to identify data that deviate from historical patterns. The method first built a forecasting model on the history data and then used it to predict future values. Anomalies are assumed to take place if the observed values fall outside a given prediction confidence interval (PCI), which can be calculated by the predicted value and confidence coefficient. The use of PCI as threshold is mainly on the fact that it considers the uncertainty in the data series parameters in the forecasting model to address the suitable threshold selection problem. The method performs fast, incremental evaluation of data as it becomes available, scales to large quantities of data, and requires no preclassification of anomalies. Experiments with different hydrologic real-world time series showed that the proposed methods are fast and correctly identify abnormal data and can be used for hydrologic time series analysis

Enzyme-mediated dual-targeted-assembly realizes a synergistic anticancer effect

We designed and synthesized homochiral-peptide-based boron diketonate complexes. Co-administration of the two stereoisomers in cancer cells led to molecular assembly targeting both the plasma membrane and the lysosomes mediated via membrane-bonded enzymes. The dual-targeted-assembly generates a synergistic anticancer effect with amplified cancer spheroid toxicity and enhanced inhibition efficacy on cancer cell migration